Sydney West Translational Cancer Research Centre
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2D VS 3D cell culture systems -Which is better?



Children's Medical Research Institute

The use of 3D cell cultures has been rising sharply in recent years from its initial introduction, over two decades ago. Because 3D cultures more accurately mimic the cellular environment, they can be used to study various forms of cancer by fostering the growth of organoidsthat replicate key properties of in vivo organ systems or the original tumors from which they were derived.
In addition, many 3D cultures are amenable to large-scale drug screens for rapid detection of phenotypic or genetic changes associated with therapeutic compounds—an approach that opens the door for the use of 3D culture as an integral part of personalized medicine.

Please join us to review some examples and procedures: where evidence strongly suggests that 3D cell cultures establish physiological cell-cell and cell-ECM interactions, and, as a result, they can mimic the specificity of native tissue with greater physiological relevance than conventional 2D cultures.
About the Presenter Ziqiu (Lisa) Guan (PhD) is the Applications Manager of Corning Life Sciences, Asia Pacific. Dr. Guan graduated from IGDB (Institute of Genetics and Developmental Biology, CAS) in 2008 with a major in Molecular Biology. Dr. Guan has worked for different companies and has great experience in drug evaluation and assay development. Dr. Guan joined Corning in 2011 as FAS and established the Corning Life Sciences Asia Technology Center in Shanghai. Dr. Guan is currently responsible for providing in-depth technical and application support to help researchers to simplify their workflow with Corning latest products and technology.

Please register your interest before the seminar: Caiyan WU: [email protected] More information on: 3D cell culture website